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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN1
All Species:
30.61
Human Site:
T165
Identified Species:
51.79
UniProt:
Q16512
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16512
NP_002732.3
942
103932
T165
K
D
R
K
L
L
L
T
A
Q
Q
M
L
Q
D
Chimpanzee
Pan troglodytes
XP_512443
1169
127241
T392
K
D
R
K
L
L
L
T
A
Q
Q
M
L
Q
D
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
A257
K
E
R
K
L
L
A
A
A
Q
Q
M
L
R
D
Dog
Lupus familis
XP_542019
1076
118222
T298
K
D
R
K
L
L
L
T
A
Q
Q
M
L
Q
D
Cat
Felis silvestris
Mouse
Mus musculus
P70268
946
104392
T165
K
D
R
K
L
L
L
T
A
Q
Q
M
L
Q
D
Rat
Rattus norvegicus
Q63433
946
104449
T165
K
D
R
K
L
L
L
T
A
Q
Q
M
L
Q
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
T244
K
E
R
K
L
V
A
T
A
Q
Q
M
L
G
D
Chicken
Gallus gallus
XP_422357
1013
114806
T202
K
D
R
K
L
L
A
T
A
Q
Q
M
L
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689331
948
107057
T183
K
D
K
K
M
L
Q
T
A
Q
Q
M
L
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
E66
N
E
P
R
W
N
E
E
F
T
A
S
G
V
H
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
K118
I
L
R
E
G
L
E
K
R
I
Q
E
L
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
A155
G
D
Q
R
S
S
S
A
A
E
G
G
A
M
E
Red Bread Mold
Neurospora crassa
P87253
1142
127954
A200
K
K
S
K
L
D
A
A
A
K
R
V
E
S
K
Conservation
Percent
Protein Identity:
100
79.3
38.7
83
N.A.
91.6
91.9
N.A.
42.2
57.6
N.A.
66.7
N.A.
29
N.A.
27.8
48.5
Protein Similarity:
100
79.9
52.6
84.3
N.A.
94.7
94.6
N.A.
56.1
72.1
N.A.
79.5
N.A.
42.8
N.A.
43.4
61.7
P-Site Identity:
100
100
73.3
100
N.A.
100
100
N.A.
73.3
93.3
N.A.
80
N.A.
0
N.A.
0
26.6
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
93.3
N.A.
0
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.8
28.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.4
45.1
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
29
22
79
0
8
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
58
0
0
0
8
0
0
0
0
0
0
0
0
65
% D
% Glu:
0
22
0
8
0
0
15
8
0
8
0
8
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
8
0
0
0
8
0
0
0
0
0
8
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
72
8
8
72
0
0
0
8
0
8
0
0
0
0
8
% K
% Leu:
0
8
0
0
65
65
36
0
0
0
0
0
72
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
65
0
8
0
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
8
% P
% Gln:
0
0
8
0
0
0
8
0
0
65
72
0
0
50
0
% Q
% Arg:
0
0
65
15
0
0
0
0
8
0
8
0
0
8
0
% R
% Ser:
0
0
8
0
8
8
8
0
0
0
0
8
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
58
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _